Hi guys. Similar issue for me as well.
With some WARNINGS first,
~/data_ops/eks/flyte/flytesnacks/cookbook$ pyflyte run --remote core/flyte_basics/hello_world.py my_wf 
2023-05-24 15:01:01,173936 WARNING  {"asctime": "2023-05-24 15:01:01,173", "name": "flytekit", "levelname": "WARNING", "message": "Error while parsing a block mapping\n  in     file.py:185
                                    \"/home/enceladus/.flyte/config.yaml\", line 1, column 1\nexpected <block end>, but found '<block mapping start>'\n  in
                                    \"/home/enceladus/.flyte/config.yaml\", line 4, column 3 reading yaml config file at /home/enceladus/.flyte/config.yaml, ignoring..."}
2023-05-24 15:01:01,217704 WARNING  {"asctime": "2023-05-24 15:01:01,217", "name": "flytekit", "levelname": "WARNING", "message": "Error while parsing a block mapping\n  in     file.py:185
                                    \"/home/enceladus/.flyte/config.yaml\", line 1, column 1\nexpected <block end>, but found '<block mapping start>'\n  in
                                    \"/home/enceladus/.flyte/config.yaml\", line 4, column 3 reading yaml config file at /home/enceladus/.flyte/config.yaml, ignoring..."}
2023-05-24 15:01:01,221089 WARNING  {"asctime": "2023-05-24 15:01:01,221", "name": "flytekit", "levelname": "WARNING", "message": "Error while parsing a block mapping\n  in     file.py:185
                                    \"/home/enceladus/.flyte/config.yaml\", line 1, column 1\nexpected <block end>, but found '<block mapping start>'\n  in
                                    \"/home/enceladus/.flyte/config.yaml\", line 4, column 3 reading yaml config file at /home/enceladus/.flyte/config.yaml, ignoring..."}
2023-05-24 15:01:02,057700 WARNING  {"asctime": "2023-05-24 15:01:02,057", "name": "flytekit", "levelname": "WARNING", "message": "Error while parsing a block mapping\n  in     file.py:185
                                    \"/home/enceladus/.flyte/config.yaml\", line 1, column 1\nexpected <block end>, but found '<block mapping start>'\n  in
                                    \"/home/enceladus/.flyte/config.yaml\", line 4, column 3 reading yaml config file at /home/enceladus/.flyte/config.yaml, ignoring..."}
2023-05-24 15:01:02,060970 WARNING  {"asctime": "2023-05-24 15:01:02,060", "name": "flytekit", "levelname": "WARNING", "message": "Error while parsing a block mapping\n  in     file.py:185
                                    \"/home/enceladus/.flyte/config.yaml\", line 1, column 1\nexpected <block end>, but found '<block mapping start>'\n  in
                                    \"/home/enceladus/.flyte/config.yaml\", line 4, column 3 reading yaml config file at /home/enceladus/.flyte/config.yaml, ignoring..."}
Failed with Exception Code: SYSTEM:Unknown
RPC Failed, with Status: StatusCode.UNAVAILABLE
        details: failed to connect to all addresses; last error: UNKNOWN: ipv4:127.0.0.1:30080: Failed to connect to remote host: Connection refused
        Debug string UNKNOWN:failed to connect to all addresses; last error: UNKNOWN: ipv4:127.0.0.1:30080: Failed to connect to remote host: Connection refused {created_time:"2023-05-24T15:01:09.752070056+05:30", grpc_status:14}
heres the config -
admin:
  # For GRPC endpoints you might want to use dns:///flyte.myexample.com
        endpoint: dns:///localhost:8089
  authType: Pkce
  insecure: true
logger:
  show-source: true
  level: 0
I installed single cloud cluster flyte with latest 1.6.1 helm chart.
both http and grpc are forwarded in other terminals.
The flyte frontend is up on 8088.
any thoughts?